| Term: | integument pyroptotic inflammatory response |
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| Note: | This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name. |
| Name: | integument |
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| Synonyms: | skin |
| Definition: | The outer protective barrier that separates the animal from its aquatic environment. |
| Ontology: | Anatomy Ontology [ZFA:0000368] |
| Name: | pyroptotic inflammatory response |
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| Synonyms: | pyroptosis |
| Definition: | A gasdermin-dependent inflammatory response that is associated with the generation of pyrogenic mediators such as IL-1beta and IL-18. Gasdermins are activated by caspase-1 or caspase-4/11, or by certain granzymes. In some, but not all cells, it can lead to pyroptotic programmed cell death. |
| Ontology: | GO: Biological Process [GO:0070269] QuickGO AmiGO |