| Term: | Mauthner neuron NMDA glutamate receptor activity |
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| Note: | This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name. |
| Name: | Mauthner neuron |
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| Synonyms: | |
| Definition: | Is a hindbrain interneuron. Giant reticulospinal neurons possessing thick crossed axons and positioned dorsally in the hindbrain tegmentum at the level of entrance of the eighth cranial nerve. The Mauthner neuron is paired. The M-cell has two large invariant dendrites: The lateral dendrite terminates in the sensory neuropil of the acoustico-lateral area, and the ventral dendrite terminates in the neuropil of the motor tegmentum. Fine dendrites are present, and mostly arise from three regions; from the terminus of each major dendrite and from the ventral surface of the perikaryon. |
| Ontology: | Anatomy Ontology [ZFA:0009149] |
| Name: | NMDA glutamate receptor activity |
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| Synonyms: | N-methyl-D-aspartate selective glutamate receptor activity, NMDA receptor |
| Definition: | A cation channel that opens in response to binding by extracellular glutmate, but only if glycine or D-serine is also bound and the membrane is depolarized. Voltage gating is indirect, due to ejection of bound magnesium from the pore at permissive voltages. |
| Ontology: | GO: Molecular Function [GO:0004972] QuickGO AmiGO |