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Phenotype Figure Summary
Marker:
ddx46
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Hirabayashi
et al.
, 2013
Fig. 1
ddx46
hi2137Tg/hi2137Tg
definitive hemopoiesis decreased occurrence, abnormal
hematopoietic stem cell
myb
expression decreased amount, abnormal
hematopoietic stem cell
runx1
expression decreased amount, abnormal
hematopoietic stem cell
tal1
expression decreased amount, abnormal
Fig. 4
ddx46
hi2137Tg/hi2137Tg
blood island hematopoietic stem cell decreased amount, abnormal
hematopoietic stem cell
myb
expression decreased distribution, abnormal
hematopoietic stem cell decreased amount, abnormal
intermediate cell mass of mesoderm hematopoietic stem cell
myb
expression decreased distribution, abnormal
ventral wall of dorsal aorta hematopoietic stem cell
myb
expression decreased distribution, abnormal
ventral wall of dorsal aorta hematopoietic stem cell decreased amount, abnormal
Fig. 7
ddx46
hi2137Tg/hi2137Tg
erythroid lineage cell
hbae1.1
expression decreased amount, abnormal
thymus lymphoid progenitor cell
ikzf1
expression absent, abnormal
thymus lymphoid progenitor cell
rag1
expression absent, abnormal
Fig. 8
ddx46
hi2137Tg/hi2137Tg
hematopoietic system posterior region
gata1a
expression decreased amount, abnormal
mRNA splicing, via spliceosome decreased occurrence, abnormal
whole organism
gata1a
expression decreased amount, abnormal
Hozumi
et al.
, 2012
Fig. 1
ddx46
ha4/ha4
(AB)
brain apoptotic, abnormal
exocrine pancreas decreased size, abnormal
intestinal epithelium decreased thickness, abnormal
intestinal epithelium smooth, abnormal
liver decreased size, abnormal
posterior intestine apoptotic, abnormal
retina apoptotic, abnormal
retina decreased size, abnormal
swim bladder inflation arrested, abnormal
Fig. 3
ddx46
hi2137Tg/hi2137Tg
, 
ddx46
ha4/ha4
(AB)
exocrine pancreas decreased size, abnormal
Fig. 5
ddx46
hi2137Tg/hi2137Tg
exocrine pancreas decreased size, abnormal
intestinal epithelium decreased thickness, abnormal
liver decreased size, abnormal
Fig. 6
ddx46
hi2137Tg/hi2137Tg
mRNA splicing, via spliceosome process quality, abnormal
Fig. S1
ddx46
ha4/ha4
(AB)
exocrine pancreas decreased size, abnormal
Fig. S3
ddx46
ha4/+
; ddx46
hi2137Tg/+
intestinal epithelium smooth, abnormal
retina decreased size, abnormal
swim bladder inflation arrested, abnormal
Fig. S6
ddx46
ha4/ha4
(AB)
exocrine pancreas decreased size, abnormal
liver decreased size, abnormal
Fig. S7
ddx46
ha4/+
; ddx46
hi2137Tg/+
exocrine pancreas decreased size, abnormal
liver decreased size, abnormal
Fig. S9
ddx46
hi2137Tg/hi2137Tg
mRNA splicing, via spliceosome process quality, abnormal
Phenotype Annotation (1994-2006)
Fig. for (hi2137)
ddx46
hi2137Tg
eye decreased size, abnormal
gut quality, abnormal
head quality, abnormal
heart quality, abnormal
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