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Phenotype Figure Summary
Marker:
plk1
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Abrams
et al.
, 2020
Fig. 7
plk1
p09ajug/p09ajug
embryonic cleavage asynchronous, abnormal
Hu
et al.
, 2019
Fig. 1
plk1
tju2/tju2
(TU)
eye decreased size, abnormal
Fig. 2
plk1
tju2/tju2
(TU)
eye decreased size, abnormal
lens decreased size, abnormal
lens development in camera-type eye decreased process quality, abnormal
retina disorganized, abnormal
retina morphology, abnormal
Fig. 5
plk1
tju2/tju2
(TU)
neural tube cilium assembly decreased occurrence, abnormal
neural tube cilium decreased amount, abnormal
Fig. S2
plk1
tju2/tju2
(TU)
caudal fin necrotic, abnormal
eye decreased size, abnormal
whole organism developmental process decreased occurrence, abnormal
Fig. S5
plk1
tju2/tju2
(TU)
eye
plk1
expression decreased amount, abnormal
Swartz
et al.
, 2014
Fig. 4
plk1
hi1856Tg/hi1856Tg
eye decreased size, abnormal
head decreased size, abnormal
neurocranium malformed, abnormal
splanchnocranium hypoplastic, abnormal
Fig. 5
plk1
hi1856Tg/hi1856Tg
apoptotic process increased process quality, abnormal
cranial nerve neuron projection physical object quality, abnormal
Jeong
et al.
, 2010
Fig. 2
WT + MO2-plk1
integument fragile, abnormal
median fin fold apoptotic, abnormal
spinal cord apoptotic, abnormal
tail bud apoptotic, abnormal
whole organism decreased size, abnormal
Fig. 3
WT + MO2-plk1
cell centrosome position, abnormal
cell centrosome variability of size, abnormal
cell mitotic spindle disorganized, abnormal
mitotic cell cycle, embryonic disrupted, abnormal
mitotic centrosome separation disrupted, abnormal
mitotic metaphase chromosome alignment disrupted, abnormal
mitotic prometaphase arrested, abnormal
mitotic spindle assembly disrupted, abnormal
Fig. 4
WT + MO2-plk1
chromosome condensation increased occurrence, abnormal
mitotic sister chromatid separation disrupted, abnormal
Fig. 5
snu1Tg + MO2-plk1
mitotic cell cycle, embryonic disrupted, abnormal
mitotic metaphase chromosome alignment disrupted, abnormal
mitotic sister chromatid separation disrupted, abnormal
text only
WT + MO3-plk1
mitotic cell cycle, embryonic disrupted, abnormal
Zhong
et al.
, 2010
Fig. 3
TU + MO1-plk1
brain structure, abnormal
head decreased size, abnormal
head deformed, abnormal
whole organism decreased length, abnormal
Fig. 5
TU + MO1-plk1
head decreased size, abnormal
head deformed, abnormal
Fig. S10
zf35Tg + MO1-plk1
neuron decreased amount, abnormal
Phenotype Annotation (1994-2006)
Fig. for (hi1856)
plk1
hi1856Tg
brain necrotic, abnormal
eye decreased size, abnormal
heart quality, abnormal
Amsterdam
et al.
, 2004
text only
plk1
hi1856Tg/hi1856Tg
central nervous system necrotic, abnormal
eye decreased size, abnormal
head decreased size, abnormal
pericardium edematous, abnormal
trunk decreased thickness, abnormal
trunk degenerate, abnormal
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