Publication	Data		Fish	Anatomy
Shao et al., 2022	Fig. 6		insraihb357/ihb357	whole organism glucose increased amount, abnormal
Qi et al., 2021	Figure 5		y1Tg + MO3-insra	hyaloid vessel increased branchiness, abnormal hyaloid vessel sprouting angiogenesis increased process quality, abnormal whole organism glucose increased amount, abnormal
Gong et al., 2018	Fig. 1		insraihb357/ihb357	blood glucose increased amount, abnormal whole organism increased length, abnormal whole organism increased weight, abnormal
	Fig. 2		insraihb357/ihb357	liver gck expression decreased amount, abnormal liver hk1 expression decreased amount, abnormal liver ldha expression increased amount, abnormal liver pfklb expression decreased amount, abnormal liver pfklb expression increased amount, abnormal liver pklr expression decreased amount, abnormal
	Fig. 3		insraihb357/ihb357	liver pyruvate kinase activity decreased occurrence, abnormal liver pyruvate kinase activity increased occurrence, abnormal
	Fig. 4		insraihb357/ihb357	muscle gck expression decreased amount, abnormal muscle hk1 expression decreased amount, abnormal muscle ldha expression decreased amount, abnormal muscle ldha expression increased amount, abnormal muscle pfkma expression decreased amount, abnormal muscle pyruvate kinase activity decreased occurrence, abnormal
	Fig. 5		insraihb357/ihb357	liver g6pc1a.1 expression increased amount, abnormal liver pck1 expression decreased amount, abnormal liver pck1 expression increased amount, abnormal
	Fig. 6		insraihb357/ihb357	liver glucose-6-phosphatase activity decreased occurrence, abnormal liver glucose-6-phosphatase activity increased occurrence, abnormal liver phosphoenolpyruvate carboxykinase activity increased occurrence, abnormal
	Fig. 7		insraihb357/ihb357	blood plasma insulin increased amount, abnormal liver ab5-akt labeling decreased amount, abnormal
	Fig. 8		insraihb357/ihb357	blood glucose increased amount, abnormal glucose-6-phosphatase activity increased occurrence, abnormal phosphoenolpyruvate carboxykinase activity increased occurrence, abnormal whole organism foxo1a expression increased amount, abnormal whole organism g6pc1a.1 expression increased amount, abnormal whole organism pck1 expression increased amount, abnormal
Riddle et al., 2018	Fig. 3		insrapsi101/psi101	whole organism increased length, abnormal whole organism increased weight, abnormal
	Fig. S8		insrapsi101/psi101	fin scale decreased size, abnormal scale growth disrupted, abnormal
Yang et al., 2017	Fig. 3		insraihb357/ihb357	whole organism glucose decreased amount, abnormal
	Fig. 6		insraihb357/ihb357	digestive system g6pc1a.1 expression increased amount, abnormal digestive system gck expression decreased amount, abnormal whole organism g6pc1a.1 expression increased amount, abnormal whole organism gck expression decreased amount, abnormal whole organism hkdc1 expression decreased amount, abnormal whole organism idh3b expression decreased amount, abnormal whole organism pklr expression decreased amount, abnormal
Yang et al., 2017	Fig. 1		insraihb357/ihb357	blood glucose increased amount, abnormal liver aldoaa expression decreased amount, abnormal liver g6pc1a.1 expression decreased amount, abnormal liver gck expression decreased amount, abnormal liver gpia expression decreased amount, abnormal liver hkdc1 expression decreased amount, abnormal liver pklr expression decreased amount, abnormal liver Ab1-gck labeling decreased amount, abnormal liver ab5-akt labeling decreased amount, abnormal
	Fig. 2		insraihb357/ihb357	feeding behavior increased rate, abnormal liver Ab3-prkaa labeling decreased amount, abnormal
	Fig. 3		insraihb357/ihb357	liver lipid decreased amount, abnormal
	Fig. 4		insraihb357/ihb357	blood plasma cholesterol decreased amount, abnormal blood plasma fatty acid decreased amount, abnormal blood plasma phospholipid decreased amount, abnormal blood plasma triglyceride decreased amount, abnormal liver triglyceride decreased amount, abnormal
	Fig. 5		insraihb357/ihb357	liver Ab1-igf1 labeling increased amount, abnormal liver Ab2-ppara labeling increased amount, abnormal muscle ab1-rps6 labeling increased amount, abnormal muscle ab3-stat5 labeling increased amount, abnormal
	Fig. 6		insraihb357/ihb357	adipose tissue fas expression decreased amount, abnormal adipose tissue pparg expression decreased amount, abnormal liver acaca expression decreased amount, abnormal liver acsl1b expression increased amount, abnormal liver cpt1b expression increased amount, abnormal liver elovl5 expression decreased amount, abnormal liver fabp1a expression decreased amount, abnormal liver fads2 expression decreased amount, abnormal liver fas expression decreased amount, abnormal liver foxo1a expression increased amount, abnormal liver lipca expression decreased amount, abnormal liver mknk2b expression decreased amount, abnormal liver pygmb expression decreased amount, abnormal liver shc2 expression increased amount, abnormal liver socs1a expression increased amount, abnormal liver socs2 expression increased amount, abnormal muscle bcat1 expression increased amount, abnormal muscle eif4ebp1 expression increased amount, abnormal muscle igf1 expression increased amount, abnormal muscle igf1rb expression increased amount, abnormal muscle mat2aa expression increased amount, abnormal muscle stat1b expression increased amount, abnormal muscle ulk2 expression increased amount, abnormal
Toyoshima et al., 2008	Fig. 6		WT + MO1-insra	eye decreased size, abnormal forebrain decreased size, abnormal growth disrupted, abnormal midbrain decreased size, abnormal midbrain hindbrain boundary deformed, abnormal post-vent region curved, abnormal