Genomic Feature
u517
- ID
- ZDB-ALT-210920-13
- Name
- u517
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one deletion (1)
- Protocol
- embryos treated with
- Lab of Origin
- Steve Wilson Lab
- Current Source
- Other Pages
-
Notes
No data available
Variants
- Variant Type
- Small Deletion
- Variant Location
- Chr 1: 24076751 - 24076754 (GRCz11) (1) Details
- Nucleotide change
- AGGA/-
- Variant Notes
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 4 bp deleted (1)
- Transcript Consequence
- Frameshift, Premature Stop (1)
- Protein Consequence
- Polypeptide Truncation (1)
- Flanking Sequence
-
AACAATTCCAACACTCACGGCTGAGTCTGGACAACTGCACACTGGCACACAGTTTTGACGCGCAAACACAAGTGAGAGATGATGACATGATGCGCGGAGATTCATCCTGCAGCTGATACTGGCTCGGAGAGCAAGTTAAACCCTTAAAACCTTTTTTTAAGTTGAGTTGAAGAAGTCGCACTGTCTTGGATCCATCCGTTTCCTGGTCCAAACTTGACGTCTATCCGCTGCGGGCGCAAACTTCATCATCACTTGATCTTTTGTTTTTTTGTTTTTCTTTTCCTGGGAGTTGTGCCTCTGGCTTCACCGGTAAGCATTGGATCCATCGGCGTACTGCGAAACTCCGGTCTACAGTCCGGATCTGTGCCCAAACATGATTGCAACGCAAGCAAAGCTGGTTTACCAGCTTAATAAATATTACAACGAAAGATGCCAGGCGCGCAAAGCGGCCATCGCCAAGACCATACGAGAGGTGTGTAAGGTGGTGTCGGATGTGCTGA
AGGA/- GGTGGAGGTCCAAGAGCCCCGTTTCATCAGCTCCCTGAGCGAGATAGACGCGCGCTATGAGGGCATGGAGGTCATCGCACCCAACGAGTTTGAGGTCGTACTTTACCTGAACCAGATGGGGGTGTTCAACTTTGTAGACGATGGCTCTCTGCCGGGCTGCGCGGTGCTCAAGCTCAGCGACGGCCGCAAGAGGAGCATGTCCCTGTGGGTGGAGTTCATCACCGCCTCCGGTTATCTATCGGCACGAAAGATTCGCTCCCGCTTTCAGACGCTGGTTGCCCAGGCCGTGGATAAATGCAGCTACCGGGACGTGGTTAAGATGGTGGCGGACACGAGCGAAGTGAAACTGCGCATTCGGGAGAGATACGTCGTGCAAATCACCCCGGCCTTCAAGTGCACGGGCATCTGGCCTAGGAGTGCCGCTCAGTGGCCCATGCCTCACATCCCGTGGCCCGGGCCGAACCGGGTGGCGGAGGTAAAAGCGGAGGGGTTTAACCTGC - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| mab21l2u517/u517 | Homozygous | ♀+/- ♂+/- | 3 figures from Wycliffe et al., 2020 | 3 figures from Wycliffe et al., 2020 | |
| mab21l2u517/u517; cu2Tg | Complex | Fig. 5 from Wycliffe et al., 2020 | |||
| mab21l2u517/u517; nns1Tg | Complex | 2 figures from Wycliffe et al., 2020 | 2 figures from Wycliffe et al., 2020 |
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Supplemental Information
- Genotyping protocol
- None
- Kroll, F., Powell, G.T., Ghosh, M., Gestri, G., Antinucci, P., Hearn, T.J., Tunbak, H., Lim, S., Dennis, H.W., Fernandez, J.M., Whitmore, D., Dreosti, E., Wilson, S.W., Hoffman, E.J., Rihel, J. (2021) A simple and effective F0 knockout method for rapid screening of behaviour and other complex phenotypes. eLIFE. 10:
- Wycliffe, R., Plaisancie, J., Leaman, S., Santis, O., Tucker, L., Cavieres, D., Fernandez, M., Weiss-Garrido, C., Sobarzo, C., Gestri, G., Valdivia, L.E. (2020) Developmental delay during eye morphogenesis underlies optic cup and neurogenesis defects in mab21l2u517 zebrafish mutants. The International journal of developmental biology. 65(4-5-6):289-299
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