Genomic Feature
b700
- ID
- ZDB-ALT-040701-2
- Name
- b700
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one deletion (1)
- Protocol
- ENU
- Lab of Origin
- Westerfield Lab
- Current Source
- Zebrafish International Resource Center (ZIRC) ( order this )
- Other Pages
Notes
No data available
Variants
- Variant Type
- Small Deletion
- Variant Location
- Chr 8: 3089006 - 3089027 (GRCz11) (1) Details
- Nucleotide change
- CCGGAGCGGACTTGGCGGCGTA/-
- Variant Notes
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 22 bp deleted in Exon 3 (1)
- Transcript Consequence
- Frameshift, Premature Stop (1)
- Protein Consequence
- None
- Flanking Sequence
-
TCCAATATTTAAAATACAAATACAATCTCGAATTCTAAATGATGATTGATCCAAAGGGTATGGTGGGAAGCAGCTTATTTAATGTCAGGCTCGTGAGTGGTGGGTCCACCTTCTGCTTGAAGAGTGCTGAAAGGTCACAGCTGCTCTATTCTTCCGCAGAAGGTTTTCGGTGCAGAGATGTGCCCGGTGCCACCTCGGGATCTCGGCCTCGGAAATGGTCATGAGGGCCAGGGATTTGGTGTACCACTTGAACTGTTTCACCTGCACGACTTGCAACAAAATGCTGACGACTGGGGACCACTTCGGCATGAAAGACAGTCTGGTGTACTGCAGGCTACACTTTGAAACGCTCATCCAGGGAGACTTCCCCACGCATTTCAATCACACGGATGTAGCGCCTAATAAAGGACTGAGCAGCACGGGCCCTCTAGGACTGTCTTATTATAACGGCGTGAACACAGTGCAAAAGGGCCGGCCCCGAAAGAGGAAGAGCCCTGGGC
CCGGAGCGGACTTGGCGGCGTA/- TAATGCAGGTGAGACCATCGCTCATCTTTGTGTTTTTATTGTTGCTGCTGGTTAACTGTTCTAGTTTAAAGCTTTTGTAAATATTTTTATTATTGTTTTGCACGAGGTGTAAGTGGATTTCCTCTGTGAAAAATTGCAGAACTTTTTAAAACCGCGTAGTAGTGTACGCCTTAGGGTTTACAAAAGTTTTTGGGCGTCACTTTATAAAAACCTCAATAAAATCGCGTGACGAATTTATAAAAGCAAGCTATAATGTTGAAGTTTGGTCAAAAATAATGTTAGTTATTGAACAATATTATTATTAGTTTTAAGGAATCATGGTATAATTAATTAATCGCAAATACACGTGCAAAACCTGTTTTTGGAAATACGAAAAAGGGAAAACAAATGTTTAAAAAGACGGGGAAAATAAAAAAAAAATTATCCAAACCTGACTAAAACTAACAATAGTTAACCTAATTTTAAAAATCTAGATAGAAATAATAAGCCTTAATACCTGC - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| lhx2bb700/b700 (AB, TL) | Homozygous | Unknown | Fig. for (b700) from Phenotype Annotation (1994-2006) | ||
| lhx2bb700/+ (AB) | Heterozygous | Unknown |
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Supplemental Information
- Genotyping protocol
- b700.pdf
- Peukert, D., Weber, S., Lumsden, A., and Scholpp, S. (2011) Lhx2 and lhx9 determine neuronal differentiation and compartition in the caudal forebrain by regulating wnt signaling. PLoS Biology. 9(12):e1001218
- Seth, A., Culverwell, J., Walkowicz, M., Toro, S., Rick, J.M., Neuhauss, S.C., Varga, Z.M., and Karlstrom, R.O. (2006) belladonna/(lhx2) is required for neural patterning and midline axon guidance in the zebrafish forebrain. Development (Cambridge, England). 133(4):725-735
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