| ZFIN ID: ZDB-EXP-190917-4 |
Experiment Conditions Description: chemical treatment by injection: PMX-205, resection: cardiac ventricle
| chemical treatment by injection: PMX-205 |
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| Name: | chemical treatment by injection |
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| Synonyms: | |
| Definition: | Chemical treatment in which the chemical is injected into the zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000237] |
| Name: | PMX-205 |
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| Synonyms: | (5->1)-lactam-N(2)-(1-oxo-3-phenylpropyl)-L-ornithyl-L-prolyl-3-cyclohexyl-D-alanyl-L-tryptophyl-L-arginine, C5a receptor peptide antagonist, cyclic hexapeptide complement C5a antagonist, hydrocinnamate-(orn-Pro-dcha-Trp-Arg), hydrocinnamate-cyclo(ornithyl-prolyl-D-cyclohexylalanyl-tryptophyl-arginyl), N-[(3R,6S,9S,15S,20aS)-9-(3-carbamimidamidopropyl)-3-(cyclohexylmethyl)-6-(1H-indol-3-ylmethyl)-1,4,7,10,16-pentaoxoicosahydropyrrolo[1,2-a][1,4,7,10,13]pentaazacyclooctadecin-15-yl]-3-phenylpropanamide, PMX 205, PMX205 |
| Definition: | A homodetic cyclic peptide resulting from the formal condensation of the carboxy group of N(2)-(3-phenylpropanoyl)-L-ornithyl-L-prolyl-3-cyclohexyl-D-alanyl-L-tryptophyl-L-arginine with the 5-amino group of the N(2)-acylornithyl residue. |
| Ontology: | ChEBI [CHEBI:144869] ( EBI ) |
| resection: cardiac ventricle |
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| Name: | resection |
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| Synonyms: | |
| Definition: | Surgical manipulation in which a particular organ, appendage, or part of an organism is removed. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000171] |
| Name: | cardiac ventricle |
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| Synonyms: | ventricle |
| Definition: | Cavitated compound organ that receives blood flow from the atrium and delivers blood to the body via the aorta. Valves are present to direct flow. There are only two chambers present in the fish heart. |
| Ontology: | Anatomy Ontology [ZFA:0000009] |
| Publication: | Natarajan et al., 2018 |
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