PMX-205

Term ID

CHEBI:144869

Synonyms

(5->1)-lactam-N(2)-(1-oxo-3-phenylpropyl)-L-ornithyl-L-prolyl-3-cyclohexyl-D-alanyl-L-tryptophyl-L-arginine
C5a receptor peptide antagonist
cyclic hexapeptide complement C5a antagonist
hydrocinnamate-(orn-Pro-dcha-Trp-Arg)
hydrocinnamate-cyclo(ornithyl-prolyl-D-cyclohexylalanyl-tryptophyl-arginyl)
N-[(3R,6S,9S,15S,20aS)-9-(3-carbamimidamidopropyl)-3-(cyclohexylmethyl)-6-(1H-indol-3-ylmethyl)-1,4,7,10,16-pentaoxoicosahydropyrrolo[1,2-a][1,4,7,10,13]pentaazacyclooctadecin-15-yl]-3-phenylpropanamide
PMX 205
PMX205

Definition

A homodetic cyclic peptide resulting from the formal condensation of the carboxy group of N(2)-(3-phenylpropanoyl)-L-ornithyl-L-prolyl-3-cyclohexyl-D-alanyl-L-tryptophyl-L-arginine with the 5-amino group of the N(2)-acylornithyl residue.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: azamacrocycle homodetic cyclic peptide

azamacrocycle homodetic cyclic peptide Show first 5 Terms
has_role: antagonist anti-inflammatory agent C5a receptor antagonist

antagonist anti-inflammatory agent C5a receptor antagonist Show first 5 Terms

Phenotype

Phenotype resulting from PMX-205

Phenotype where environments contain PMX-205

Phenotype modified by environments containing PMX-205

Human Disease / Model Data