Transgenic Construct
Tg(hcrt:NTR-EGFP)
- ID
- ZDB-TGCONSTRCT-121009-1
- Name
- Tg(hcrt:NTR-EGFP)
- Previous Names
-
- Tg(hcrt:Eco.NfsB-EGFP)
- Tg(hcrt:nfsB-EGFP) (1)
- Type
- engineered_plasmid
- Regulatory Regions
- Coding Sequences
- [Em λ][Ex λ]
- Fpbase:EGFP
- Contains Sequences
- Note
-
This construct is designed to drive expression of E. coli nitroreductase in the hcrt-expressing neurons of the larval hypothalamus. Bath application of the prodrug metronidazole (e.g. 15 mM from 24-72 hpf) results in cell-specific ablation of hcrt-neurons. -- Elbaz et al. 2012, ZDB-PUB-120927-25
Plasmid Map
None
Genomic Features
That Utilize Tg(hcrt:NTR-EGFP) Construct
| Genomic Feature | Affected Genomic Regions |
|---|---|
| biu01Tg |
Transgenics
That Utilize Tg(hcrt:NTR-EGFP) Construct
| Fish | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|
| biu01Tg |
|
5 figures from Elbaz et al., 2012 | 2 figures from Elbaz et al., 2012 |
Sequence Information
Other Construct Pages
None
Citations