Transgenic Construct
Tg(Mmu.Foxa2-cryaa:mCherry)
- ID
- ZDB-TGCONSTRCT-110310-3
- Name
- Tg(Mmu.Foxa2-cryaa:mCherry)
- Previous Names
-
- Tg(gli-d:mCherry) (1)
- Type
- engineered_plasmid
- Regulatory Regions
- Coding Sequences
- [Em λ][Ex λ]
- Fpbase:mCherry
- Contains Sequences
- Note
-
A Hh-pathway sensitive reporter construct, comprised of a Gli-d promoter element containing eight repeating Gli-CBS from the mouse FoxA2 floor plate enhancer and a minimal lens crystallin promoter. Gli transcription factors transduce the Hh-signal by binding to DNA in a sequence-specific manner through the recognition of the DNA motif GACCACCCA, known as the Gli-consensus binding sequence (Gli-CBS)
Plasmid Map
None
Genomic Features
That Utilize Tg(Mmu.Foxa2-cryaa:mCherry) Construct
Transgenics
That Utilize Tg(Mmu.Foxa2-cryaa:mCherry) Construct
Fish | Affected Genomic Regions | Phenotype | Gene Expression |
---|---|---|---|
af2Tg; af3Tg |
|
Fig. 2
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|
gli1ts269/ts269; nu15Tg | |||
gli2aty119/ty119; nu15Tg | |||
ia5Tg; nu15Tg; y1Tg |
|
||
ia5Tg; nu15Tg; y1Tg + MO1-mir7a |
|
Fig. S8 from Adusumilli et al., 2020 |
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Sequence Information
Other Construct Pages
None
Citations