TALEN

TALEN1-spi1b

ID

ZDB-TALEN-230410-1

Name

TALEN1-spi1b

Previous Names

None

Target

spi1b (1)

Target Sequence 1

5' - CTCTTTCAACTTCAAT - 3'

Target Sequence 2

5' - TATAATCCCAAGAGT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
hkz24	spi1b
hkz27	spi1b

Expression

Gene expression in Wild Types + TALEN1-spi1b

No data available

Phenotype

Phenotype resulting from TALEN1-spi1b

No data available

Phenotype of all Fish created by or utilizing TALEN1-spi1b

Phenotype	Fish	Conditions	Figures
common myeloid progenitor cebpa expression decreased amount, abnormal	spi1b^hkz24/hkz24	standard conditions	Fig. 1 from Yu et al., 2017
whole organism spi1a expression increased amount, abnormal	spi1b^hkz24/hkz24	standard conditions	Fig. 4 from Yu et al., 2017
central nervous system microglial cell decreased amount, abnormal	spi1b^hkz24/hkz24	standard conditions	Fig. 6 from Yu et al., 2017
macrophage decreased amount, abnormal	spi1b^hkz24/hkz24	standard conditions	Fig. 1 from Yu et al., 2017
myeloid cell irf8 expression decreased amount, abnormal	spi1b^hkz24/hkz24	standard conditions	Fig. 7 from Yu et al., 2017
macrophage mfap4.1 expression decreased amount, abnormal	spi1b^hkz24/hkz24	standard conditions	Fig. 1, Fig. 6 from Yu et al., 2017
macrophage lyz expression decreased amount, abnormal	spi1b^hkz24/hkz24	standard conditions	Fig. 1 from Yu et al., 2017
ventral wall of dorsal aorta macrophage EGFP expression increased amount, abnormal	spi1b^hkz24/hkz24; hkz015tTg/hkz015tTg	heat shock, chemical treatment by environment: tamoxifen	Fig. 1 from Yu et al., 2017
ventral wall of dorsal aorta macrophage increased amount, abnormal	spi1b^hkz24/hkz24; hkz015tTg/hkz015tTg	heat shock, chemical treatment by environment: tamoxifen	Fig. 1 from Yu et al., 2017
central nervous system microglial cell normal amount, ameliorated	spi1b^hkz24/hkz24; hkz054Tg/hkz054Tg	standard conditions	Fig. 6 from Yu et al., 2017
macrophage mfap4.1 expression amount, ameliorated	spi1b^hkz24/hkz24; hkz054Tg/hkz054Tg	standard conditions	Fig. 6 from Yu et al., 2017
central nervous system microglial cell normal amount, ameliorated	spi1b^hkz24/hkz24; hkz055Tg/hkz055Tg	standard conditions	Fig. 6 from Yu et al., 2017
macrophage mfap4.1 expression amount, ameliorated	spi1b^hkz24/hkz24; hkz055Tg/hkz055Tg	standard conditions	Fig. 6 from Yu et al., 2017
caudal hematopoietic tissue macrophage apoptotic, abnormal	spi1b^hkz24/hkz24; spi1a^hkz25/hkz25; hkz05tTg/hkz05tTg	standard conditions	Fig. 3 from Yu et al., 2017
central nervous system macrophage EGFP expression decreased amount, abnormal	spi1b^hkz24/hkz24; spi1a^hkz25/hkz25; hkz05tTg/hkz05tTg	standard conditions	Fig. 3 from Yu et al., 2017
central nervous system microglial cell decreased amount, abnormal	spi1b^hkz24/hkz24; spi1a^hkz25/hkz25; hkz015tTg/hkz015tTg	standard conditions	Fig. 3 from Yu et al., 2017
ventral wall of dorsal aorta macrophage EGFP expression decreased amount, abnormal	spi1b^hkz24/hkz24; spi1a^hkz25/hkz25; hkz015tTg/hkz015tTg	standard conditions	Fig. 3 from Yu et al., 2017
macrophage irf8 expression decreased amount, abnormal	spi1b^hkz24/hkz24; spi1a^hkz25/hkz25; hkz015tTg/hkz015tTg	standard conditions	Fig. 7 from Yu et al., 2017
caudal hematopoietic tissue macrophage apoptotic, abnormal	spi1b^hkz24/hkz24; spi1a^hkz25/hkz25; hkz015tTg/hkz015tTg	standard conditions	Fig. 3 from Yu et al., 2017
macrophage mfap4.1 expression decreased amount, abnormal	spi1b^hkz27/hkz27; spi1a^hkz25/hkz25	standard conditions	Fig. 5 from Yu et al., 2017
macrophage decreased amount, abnormal	spi1b^hkz27/hkz27; spi1a^hkz25/hkz25	standard conditions	Fig. 5 from Yu et al., 2017

Citations