Gene
spi1b
- ID
- ZDB-GENE-980526-164
- Name
- Spi-1 proto-oncogene b
- Symbol
- spi1b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Exhibits sequence-specific DNA binding activity. Involved in myeloid cell differentiation; negative regulation of myeloid cell differentiation; and positive regulation of gene expression. Predicted to localize to nucleus. Is expressed in several structures, including hematopoietic cell; hematopoietic system; mesoderm; trunk; and yolk. Orthologous to human SPI1 (Spi-1 proto-oncogene).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 234 figures from 157 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb1086 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- 40 figures from 30 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| agammaglobulinemia 10 | Alliance | Agammaglobulinemia 10, autosomal dominant | 619707 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Ets domain | ETS family | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:F1R668
|
266 | ||||
|
UniProtKB:Q78AM8
|
296 | ||||
|
UniProtKB:A0A8M2BG46
|
297 | ||||
|
UniProtKB:Q8AW41
|
265 |
Interactions and Pathways
No data available
Plasmids
No data available