TALEN

TALEN1-yap1

ID
ZDB-TALEN-151218-1
Name
TALEN1-yap1
Previous Names
None
Target
Target Sequence 1
5' - TGAGGTTGAGAAAGCTG - 3'
ZFIN BLAST NCBI BLAST Ensembl
Target Sequence 2
5' - TTTGGCTCTGGCGGCGT - 3'
ZFIN BLAST NCBI BLAST Ensembl
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
mw48 yap1
mw69 yap1
Expression
Gene expression in Wild Types + TALEN1-yap1
No data available
Phenotype
Phenotype resulting from TALEN1-yap1
No data available
Phenotype of all Fish created by or utilizing TALEN1-yap1
Phenotype Fish Conditions Figures
whole organism hhex expression decreased amount, abnormal yap1mw48/mw48 standard conditions Fig. 2 from Cox et al., 2018
liver prox1a expression decreased amount, abnormal yap1mw48/mw48 standard conditions Fig. 3 from Cox et al., 2018
whole organism decreased size, abnormal yap1mw48/mw48 standard conditions Fig. S3 from Cox et al., 2018
exocrine pancreas decreased size, abnormal yap1mw48/mw48 standard conditions Fig. S1 from Cox et al., 2018
neuromast support cell cell population proliferation increased occurrence, abnormal yap1mw48/mw48 heat shock, chemical treatment by environment: LY-411575, chemical treatment by environment: neomycin Figure 6 with image from Ye et al., 2020
whole organism prox1a expression decreased amount, abnormal yap1mw48/mw48 standard conditions Fig. 2 from Cox et al., 2018
liver hhex expression decreased amount, abnormal yap1mw48/mw48 standard conditions Fig. 3 from Cox et al., 2018
pericardium edematous, abnormal yap1mw48/mw48 standard conditions Fig. S1 from Cox et al., 2018
whole organism slc2a2 expression decreased amount, abnormal yap1mw48/mw48 standard conditions Fig. 4 from Cox et al., 2018
blood glucose increased amount, abnormal yap1mw48/mw48 chemical treatment by injection: glucose, fasting Fig. 5 from Cox et al., 2018
retinal pigment epithelium development process quality, abnormal yap1mw48/mw48 standard conditions Fig. 1 with image,  Fig. 5 with image from Miesfeld et al., 2015
liver hepatocyte decreased amount, abnormal yap1mw48/mw48 standard conditions Fig. S1 from Cox et al., 2018
liver slc2a2 expression decreased amount, abnormal yap1mw48/mw48 standard conditions Fig. 4 from Cox et al., 2018
liver decreased size, abnormal yap1mw48/mw48 standard conditions Fig. 2,  Fig. 3,  Fig. S1,  Fig. S3 from Cox et al., 2018
liver slc2a1a expression decreased amount, abnormal yap1mw48/mw48 standard conditions Fig. 4 from Cox et al., 2018
heart edematous, abnormal yap1mw48/mw48 standard conditions Fig. 1 with image from Miesfeld et al., 2015
whole organism slc2a1a expression decreased amount, abnormal yap1mw48/mw48 standard conditions Fig. 4 from Cox et al., 2018
retinal neural layer malformed, abnormal yap1mw48/mw48 standard conditions Fig. 1 with image from Miesfeld et al., 2015
vasculature hemorrhagic, abnormal yap1mw48/mw48 standard conditions Fig. 1 with image from Miesfeld et al., 2015
whole organism decreased mass, abnormal yap1mw48/mw48 standard conditions Fig. 3 from Cox et al., 2018
intestine decreased size, abnormal yap1mw48/mw48 standard conditions Fig. S1 from Cox et al., 2018
retinal pigmented epithelium absent, abnormal yap1mw48/mw48 standard conditions Fig. 1 with image,  Fig. 5 with image from Miesfeld et al., 2015
retinal pigmented epithelium malformed, abnormal yap1mw48/mw48 standard conditions Fig. 1 with image from Miesfeld et al., 2015
liver glycogen decreased amount, abnormal yap1mw48/mw48 standard conditions Fig. S3 from Cox et al., 2018
liver hepatocyte ballooning, abnormal yap1mw48/mw48 standard conditions Fig. S1 from Cox et al., 2018
neuromast support cell cell population proliferation decreased occurrence, abnormal yap1mw48/mw48 chemical treatment by environment: LY-411575, chemical treatment by environment: neomycin Figure 3. with image from Ye et al., 2020
retinal pigment epithelium development process quality, abnormal yap1mw69/mw69 standard conditions Fig. 5 with image from Miesfeld et al., 2015
retinal pigmented epithelium absent, abnormal yap1mw69/mw69 standard conditions Fig. 5 with image from Miesfeld et al., 2015
neuromast support cell cell population proliferation increased occurrence, exacerbated yap1mw48; sqet20Et; sqet4Et heat shock, chemical treatment by environment: neomycin Figure 4 with image from Ye et al., 2020
neuromast support cell cell population proliferation increased occurrence, exacerbated yap1mw48; sqet20Et; sqet4Et heat shock Figure 4 with image from Ye et al., 2020
common bile duct morphology, ameliorated stk3mw96/mw96; yap1mw48/mw48 standard conditions Fig. S8 from Brandt et al., 2020
gall bladder morphology, ameliorated stk3mw96/mw96; yap1mw48/mw48 standard conditions Fig. S8 from Brandt et al., 2020
heart edematous, abnormal wwtr1mw49/+; yap1mw48/mw48 standard conditions Fig. 1 with image from Miesfeld et al., 2015
retinal neural layer malformed, abnormal wwtr1mw49/+; yap1mw48/mw48 standard conditions Fig. 1 with image from Miesfeld et al., 2015
vasculature hemorrhagic, abnormal wwtr1mw49/+; yap1mw48/mw48 standard conditions Fig. 1 with image from Miesfeld et al., 2015
retinal pigment epithelium development process quality, abnormal wwtr1mw49/+; yap1mw48/mw48 standard conditions Fig. 1 with image from Miesfeld et al., 2015
retinal pigmented epithelium absent, abnormal wwtr1mw49/+; yap1mw48/mw48 standard conditions Fig. 1 with image from Miesfeld et al., 2015
retinal pigmented epithelium malformed, abnormal wwtr1mw49/+; yap1mw48/mw48 standard conditions Fig. 1 with image from Miesfeld et al., 2015
head krt4 expression decreased amount, abnormal wwtr1mw49/mw49; yap1mw48/mw48 standard conditions Fig. 7 with image from Buono et al., 2021
head krt8 expression decreased amount, abnormal wwtr1mw49/mw49; yap1mw48/mw48 standard conditions Fig. 7 with image from Buono et al., 2021
head tyr expression decreased amount, abnormal wwtr1mw49/mw49; yap1mw48/mw48 standard conditions Fig. 7 with image from Buono et al., 2021
head tyrp1b expression decreased amount, abnormal wwtr1mw49/mw49; yap1mw48/mw48 standard conditions Fig. 7 with image from Buono et al., 2021
embryo development arrested, abnormal wwtr1mw49/mw49; yap1mw48/mw48 standard conditions Fig. 1 with image from Miesfeld et al., 2015
hepatocyte decreased size, abnormal yap1mw48/mw48; s931Tg standard conditions Fig. 3 from Cox et al., 2018
liver hepatocyte ballooning, abnormal yap1mw48/mw48; s931Tg standard conditions Fig. 1 from Cox et al., 2018
liver decreased area, abnormal yap1mw48/mw48; s931Tg standard conditions Fig. 1,  Fig. S1 from Cox et al., 2018
liver hepatocyte decreased amount, abnormal yap1mw48/mw48; s931Tg standard conditions Fig. 1 from Cox et al., 2018
liver decreased size, abnormal yap1mw48/mw48; s931Tg standard conditions Fig. 3,  Fig. S1 from Cox et al., 2018
Citations
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