TALEN

TALEN1-foxc1a

ID

ZDB-TALEN-150624-1

Name

TALEN1-foxc1a

Previous Names

None

Target

foxc1a (1)

Target Sequence 1

5' - ATAACACCCACGTTGT - 3'

Target Sequence 2

5' - ACACGGACGACTGATT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
nju18	foxc1a

Expression

Gene expression in Wild Types + TALEN1-foxc1a

No data available

Phenotype

Phenotype resulting from TALEN1-foxc1a

No data available

Phenotype of all Fish created by or utilizing TALEN1-foxc1a

Phenotype	Fish	Conditions	Figures
heart nkx2.5 expression decreased amount, abnormal	foxc1a^nju18/nju18	standard conditions	Fig. S4 from He et al., 2021
heart neurod1 expression decreased amount, abnormal	foxc1a^nju18/nju18	standard conditions	Fig. 3 from He et al., 2021
heart pkd2 expression decreased amount, abnormal	foxc1a^nju18/nju18	standard conditions	Fig. 3 from He et al., 2021
heart epas1b expression decreased amount, abnormal	foxc1a^nju18/nju18	standard conditions	Fig. 3 from He et al., 2021
paraxial mesoderm Notch signaling pathway decreased process quality, abnormal	foxc1a^nju18/nju18	standard conditions	Fig. 4 from Li et al., 2015
heart mecom expression decreased amount, abnormal	foxc1a^nju18/nju18	standard conditions	Fig. 3 from He et al., 2021
heart edematous, abnormal	foxc1a^nju18/nju18	standard conditions	Fig. 5 from He et al., 2021 Fig. 2 from Li et al., 2015
somitogenesis process quality, abnormal	foxc1a^nju18/nju18	standard conditions	Fig. 2, Fig. 3 from Li et al., 2015
paraxial mesoderm fibroblast growth factor receptor signaling pathway decreased process quality, abnormal	foxc1a^nju18/nju18	standard conditions	Fig. 4 from Li et al., 2015
whole organism decreased length, abnormal	foxc1a^nju18/nju18	standard conditions	Fig. 2 from Li et al., 2015
heart fezf2 expression increased amount, abnormal	foxc1a^nju18/nju18	standard conditions	Fig. 3 from He et al., 2021
heart wwtr1 expression decreased amount, abnormal	foxc1a^nju18/nju18	standard conditions	Fig. 3 from He et al., 2021
somite decreased size, abnormal	foxc1a^nju18/nju18	standard conditions	Fig. 2 from Li et al., 2015
trabecular layer of ventricle smooth, abnormal	foxc1a^nju18/nju18; f1Tg	standard conditions	Fig. 1 from He et al., 2021
heart contraction decreased spatial extent of a process, abnormal	foxc1a^nju18/nju18; f1Tg	standard conditions	Fig. 5 from He et al., 2021
cardiac ventricle ventricular trabecula myocardium morphogenesis decreased process quality, abnormal	foxc1a^nju18/nju18; f1Tg	standard conditions	Fig. 1 from He et al., 2021
cardiac ventricle has fewer parts of type cardiac muscle cell, abnormal	foxc1a^nju18/nju18; zf3348Tg	standard conditions	Fig. 1 from He et al., 2021
cardiac ventricle cell proliferation involved in heart morphogenesis decreased process quality, abnormal	foxc1a^nju18/nju18; zf3348Tg	standard conditions	Fig. 1 from He et al., 2021

Citations