TALEN

TALEN1-pdgfrb

ID
ZDB-TALEN-150403-5
Name
TALEN1-pdgfrb
Previous Names
None
Target
Target Sequence 1
5' - GGAGCTCAGTCCCAGCG - 3'
ZFIN BLAST NCBI BLAST Ensembl
Target Sequence 2
5' - GGAGGACGAGTTGATGGA - 3'
ZFIN BLAST NCBI BLAST Ensembl
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
um148 pdgfrb
Expression
Gene expression in Wild Types + TALEN1-pdgfrb
No data available
Phenotype
Phenotype resulting from TALEN1-pdgfrb
No data available
Phenotype of all Fish created by or utilizing TALEN1-pdgfrb
Phenotype Fish Conditions Figures
pronephric glomerulus lacks all parts of type mesangial cell, abnormal pdgfrbum148/um148 standard conditions Fig. 6 from Ando et al., 2021
anatomical structure pdgfrb expression decreased distribution, abnormal pdgfrbum148/um148 standard conditions Fig. 2 with image from Kok et al., 2015
central artery lacks parts or has fewer parts of type pericyte, abnormal pdgfrbum148/um148 standard conditions Fig. 1 from Ando et al., 2021
pronephric glomerular capillary dilated, abnormal pdgfrbum148/um148 standard conditions Fig. 6 from Ando et al., 2021
brain vasculature hemorrhagic, abnormal pdgfrbum148/um148 standard conditions Fig. 2 from Ando et al., 2021
pronephros development decreased process quality, abnormal pdgfrbum148/um148 standard conditions Fig. 6 from Ando et al., 2021
whole organism pdgfrb expression decreased amount, abnormal pdgfrbum148/+; y1Tg standard conditions Fig. 2 with image from Kok et al., 2015
cardiac ventricle blood vessel endothelial cell EGFP expression decreased amount, abnormal pdgfrbum148/+; y1Tg/y1Tg standard conditions Fig. 2 with image from Kapuria et al., 2022
cardiac ventricle blood vessel endothelial cell EGFP expression spatial pattern, abnormal pdgfrbum148/+; y1Tg/y1Tg standard conditions Fig. 2 with image from Kapuria et al., 2022
posterior communicating artery lacks parts or has fewer parts of type vascular associated smooth muscle cell, abnormal pdgfrbum148/um148; ca8Tg standard conditions Fig. 3 from Ando et al., 2021
basal communicating artery lacks parts or has fewer parts of type vascular associated smooth muscle cell, abnormal pdgfrbum148/um148; ca8Tg standard conditions Fig. 3 from Ando et al., 2021
brain vasculature lacks parts or has fewer parts of type vascular associated smooth muscle cell, abnormal pdgfrbum148/um148; ca8Tg; y1Tg standard conditions Fig. 2 from Ando et al., 2021
optic tectum mCherry expression absent, abnormal pdgfrbum148/um148; ca8Tg; y1Tg standard conditions Fig. 2 from Ando et al., 2021
coronary vein mural cell DsRedx expression decreased amount, abnormal pdgfrbum148/um148; mu105Tg/mu105Tg; ncv22Tg/ncv22Tg; um13Tg/um13Tg standard conditions Fig. 3 with image from Kapuria et al., 2022
coronary artery Citrine expression decreased amount, abnormal pdgfrbum148/um148; mu105Tg/mu105Tg; ncv22Tg/ncv22Tg; um13Tg/um13Tg standard conditions Fig. 3 with image from Kapuria et al., 2022
coronary artery Citrine expression spatial pattern, abnormal pdgfrbum148/um148; mu105Tg/mu105Tg; ncv22Tg/ncv22Tg; um13Tg/um13Tg standard conditions Fig. 3 with image from Kapuria et al., 2022
coronary vein mural cell EGFP expression decreased amount, abnormal pdgfrbum148/um148; mu105Tg/mu105Tg; ncv22Tg/ncv22Tg; um13Tg/um13Tg standard conditions Fig. 3 with image from Kapuria et al., 2022
regenerating tissue mural cell decreased amount, abnormal pdgfrbum148/um148; ncv22Tg/ncv22Tg; um13Tg/um13Tg amputation: heart Fig. 6 with image from Kapuria et al., 2022
cardiac ventricle mural cell EGFP expression decreased amount, abnormal pdgfrbum148/um148; ncv22Tg/ncv22Tg; um13Tg/um13Tg standard conditions Fig. 2 with image from Kapuria et al., 2022
cardiac ventricle blood vessel endothelial cell mCherry expression decreased amount, abnormal pdgfrbum148/um148; ncv22Tg/ncv22Tg; um13Tg/um13Tg standard conditions Fig. 2 with image from Kapuria et al., 2022
cardiac ventricle blood vessel endothelial cell mCherry expression spatial pattern, abnormal pdgfrbum148/um148; ncv22Tg/ncv22Tg; um13Tg/um13Tg standard conditions Fig. 2 with image from Kapuria et al., 2022
cardiac ventricle mural cell EGFP expression spatial pattern, abnormal pdgfrbum148/um148; ncv22Tg/ncv22Tg; um13Tg/um13Tg standard conditions Fig. 2 with image from Kapuria et al., 2022
regenerating tissue blood vessel remodeling decreased process quality, abnormal pdgfrbum148/um148; ncv22Tg/ncv22Tg; um13Tg/um13Tg amputation: heart Fig. 6 with image from Kapuria et al., 2022
connective tissue replacement involved in inflammatory response wound healing increased occurrence, abnormal pdgfrbum148/um148; ncv22Tg/ncv22Tg; um13Tg/um13Tg amputation: heart Fig. 6 with image from Kapuria et al., 2022
central artery lacks parts or has fewer parts of type pericyte, abnormal pdgfrbum148/um148; ncv22Tg; s896Tg standard conditions Fig. 1 from Ando et al., 2021
brain vasculature decreased volume, abnormal pdgfrbum148/um148; ncv22Tg; s896Tg standard conditions Fig. 1 from Ando et al., 2021
whole organism pdgfrb expression absent, abnormal pdgfrbum148/um148; y1Tg standard conditions Fig. 2 with image from Kok et al., 2015
cardiac ventricle blood vessel endothelial cell EGFP expression decreased amount, abnormal pdgfrbum148/um148; y1Tg/y1Tg standard conditions Fig. 2 with image from Kapuria et al., 2022
cardiac ventricle blood vessel endothelial cell EGFP expression spatial pattern, abnormal pdgfrbum148/um148; y1Tg/y1Tg standard conditions Fig. 2 with image from Kapuria et al., 2022
forebrain edematous, abnormal pdgfrab1059/b1059; pdgfrbum148/+ standard conditions Fig. 4 from Ando et al., 2021
embryonic neurocranium morphogenesis decreased process quality, abnormal pdgfrab1059/b1059; pdgfrbum148/+ standard conditions Fig. 1 with image from McCarthy et al., 2016
heart edematous, abnormal pdgfrab1059/b1059; pdgfrbum148/+ standard conditions Fig. 4 from Ando et al., 2021
trunk vasculature blood circulation decreased process quality, abnormal pdgfrab1059/b1059; pdgfrbum148/+ standard conditions Fig. 4 from Ando et al., 2021
neurocranium decreased length, abnormal pdgfrab1059/b1059; pdgfrbum148/+ standard conditions Fig. 1 with image from McCarthy et al., 2016
gut edematous, abnormal pdgfrab1059/b1059; pdgfrbum148/+ standard conditions Fig. 4 from Ando et al., 2021
brain vasculature hemorrhagic, abnormal pdgfrab1059/b1059; pdgfrbum148/+ standard conditions Fig. 4 from Ando et al., 2021
ethmoid cartilage split, abnormal pdgfrab1059/b1059; pdgfrbum148/+ standard conditions Fig. 1 with image from McCarthy et al., 2016
forebrain edematous, abnormal pdgfrab1059/b1059; pdgfrbum148/um148 standard conditions Fig. 4 from Ando et al., 2021
embryonic neurocranium morphogenesis decreased process quality, abnormal pdgfrab1059/b1059; pdgfrbum148/um148 standard conditions Fig. 1 with image from McCarthy et al., 2016
heart edematous, abnormal pdgfrab1059/b1059; pdgfrbum148/um148 standard conditions Fig. 4 from Ando et al., 2021
roof of mouth development decreased process quality, abnormal pdgfrab1059/b1059; pdgfrbum148/um148 standard conditions Fig. 1 with image from McCarthy et al., 2016
trunk vasculature blood circulation decreased process quality, abnormal pdgfrab1059/b1059; pdgfrbum148/um148 standard conditions Fig. 4 from Ando et al., 2021
neurocranium decreased length, abnormal pdgfrab1059/b1059; pdgfrbum148/um148 standard conditions Fig. 1 with image from McCarthy et al., 2016
neurocranium lacks all parts of type ethmoid cartilage, abnormal pdgfrab1059/b1059; pdgfrbum148/um148 standard conditions Fig. 1 with image from McCarthy et al., 2016
gut edematous, abnormal pdgfrab1059/b1059; pdgfrbum148/um148 standard conditions Fig. 4 from Ando et al., 2021
parachordal cartilage decreased size, abnormal pdgfrab1059/b1059; pdgfrbum148/um148 standard conditions Fig. 1 with image from McCarthy et al., 2016
brain vasculature hemorrhagic, abnormal pdgfrab1059/b1059; pdgfrbum148/um148 standard conditions Fig. 4 from Ando et al., 2021
neurocranium lacks all parts of type neurocranial trabecula, abnormal pdgfrab1059/b1059; pdgfrbum148/um148 standard conditions Fig. 1 with image from McCarthy et al., 2016
chondrocranium cartilage neural crest cell migration decreased occurrence, abnormal pdgfrab1059/b1059; pdgfrbum148/um148; y1Tg standard conditions Fig. 7 with image,  Fig. 8 with image from McCarthy et al., 2016
chondrocranium cartilage cranial neural crest cell decondensed, abnormal pdgfrab1059/b1059; pdgfrbum148/um148; y1Tg standard conditions Fig. 7 with image,  Fig. 8 with image,  Fig. 9 with image from McCarthy et al., 2016
embryonic neurocranium morphogenesis decreased process quality, abnormal pdgfrab1059/b1059; pdgfrbum148/um148; y1Tg standard conditions Fig. 7 with image,  Fig. 9 with image from McCarthy et al., 2016
roof of mouth development decreased process quality, abnormal pdgfrab1059/b1059; pdgfrbum148/um148; y1Tg standard conditions Fig. 7 with image,  Fig. 8 with image from McCarthy et al., 2016
neurocranium decreased length, abnormal pdgfrab1059/b1059; pdgfrbum148/um148; y1Tg standard conditions Fig. 8 with image,  Fig. 9 with image from McCarthy et al., 2016
Citations
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