PUBLICATION

The structure of the caudal wall of the zebrafish (Danio rerio) swim bladder: Evidence of localized lamellar body secretion and a proximate neural plexus

Authors
Robertson, G.N., Croll, R.P., Smith, F.M.
ID
ZDB-PUB-140513-319
Date
2014
Source
Journal of morphology   275(8): 933-48 (Journal)
Registered Authors
Croll, Roger P.
Keywords
autonomic nervous system, cyprinid, surfactant, ultrastructure
MeSH Terms
  • Air Sacs/enzymology
  • Air Sacs/innervation*
  • Animals
  • Epithelium
  • Extracellular Matrix/ultrastructure
  • Female
  • Fibroblasts/ultrastructure
  • Male
  • Multivesicular Bodies/ultrastructure
  • Muscle, Smooth/ultrastructure
  • Nerve Net/ultrastructure
  • Nitric Oxide Synthase Type I/metabolism
  • Secretory Vesicles/ultrastructure
  • Zebrafish/anatomy & histology*
  • Zebrafish Proteins/metabolism
PubMed
24643973 Full text @ J. Morphol.
Abstract
In this study, we present a morphological description of the fine structure of the tissues composing the caudal tip of the adult zebrafish swim bladder and an immunochemical survey of the innervation at this site. The internal aspect of the caudal tip is lined by an epithelium specialized to secrete surfactant into the lumen as evinced by the exocytosis of lamellar bodies. The sole innervation to this region consists of a neural plexus, present on the external surface, of nitric oxide synthase-positive (nNOS) neuronal cell bodies that are contacted by axon terminals, some containing neuropeptide Y and vasoactive intestinal polypeptide. As the specialized epithelium and neural plexus are coincident and of common extent, we suggest that the morphological relationship between the two elements allows the nervous system to affect surfactant processing, possibly through a paracrine mechanism.
Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping