Morpholino

MO1-sema6a

ID

ZDB-MRPHLNO-140821-3

Name

MO1-sema6a

Previous Names

None

Target

sema6a (1)

Sequence

5' - TGCTGATATCCTGCACTCACCTCAC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

Splice-blocking MO.

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-sema6a

Expressed Gene	Anatomy	Figures
dcdc2b	whole organism	Fig. 4 from Emerson et al., 2017
foxg1a	optic vesicle ventral region	Fig. 7 from Ebert et al., 2014
mmp2	whole organism	Fig. 4 from Emerson et al., 2017
rasl11b	whole organism	Fig. 4 from Emerson et al., 2017
rbl2	whole organism	Fig. 4 from Emerson et al., 2017
shtn1	whole organism	Fig. 4 from Emerson et al., 2017
vax2	optic vesicle posterior region	Fig. 7 from Ebert et al., 2014

Phenotype

Phenotype resulting from MO1-sema6a

Phenotype	Fish	Figures
eye decreased size, abnormal	zf460Tg + MO1-sema6a	Fig. 1 from Emerson et al., 2017
optic cup cell population proliferation decreased occurrence, abnormal	zf460Tg + MO1-sema6a	Fig. 1 from Emerson et al., 2017
optic vesicle decreased size, abnormal	zf460Tg + MO1-sema6a	Fig. 5 from Ebert et al., 2014
optic vesicle apoptotic process increased occurrence, abnormal	zf460Tg + MO1-sema6a	Fig. 5 from Ebert et al., 2014
optic vesicle cell mislocalised, abnormal	zf460Tg + MO1-sema6a	Fig. 5 from Ebert et al., 2014
optic vesicle regionalization decreased process quality, abnormal	WT + MO1-sema6a	Fig. 7 from Ebert et al., 2014
optic vesicle formation decreased process quality, abnormal	zf460Tg + MO1-sema6a	Fig. 5 from Ebert et al., 2014
whole organism rbl2 expression increased amount, abnormal	WT + MO1-sema6a	Fig. 4 from Emerson et al., 2017
whole organism rasl11b expression increased amount, abnormal	WT + MO1-sema6a	Fig. 4 from Emerson et al., 2017
whole organism dcdc2b expression increased amount, abnormal	WT + MO1-sema6a	Fig. 4 from Emerson et al., 2017
whole organism mmp2 expression increased amount, abnormal	WT + MO1-sema6a	Fig. 4 from Emerson et al., 2017
whole organism shtn1 expression increased amount, abnormal	WT + MO1-sema6a	Fig. 4 from Emerson et al., 2017

Phenotype of all Fish created by or utilizing MO1-sema6a

Phenotype	Fish	Conditions	Figures
whole organism dcdc2b expression increased amount, abnormal	WT + MO1-sema6a	standard conditions	Fig. 4 from Emerson et al., 2017
optic vesicle regionalization decreased process quality, abnormal	WT + MO1-sema6a	standard conditions	Fig. 7 from Ebert et al., 2014
whole organism shtn1 expression increased amount, abnormal	WT + MO1-sema6a	standard conditions	Fig. 4 from Emerson et al., 2017
whole organism rasl11b expression increased amount, abnormal	WT + MO1-sema6a	standard conditions	Fig. 4 from Emerson et al., 2017
whole organism rbl2 expression increased amount, abnormal	WT + MO1-sema6a	standard conditions	Fig. 4 from Emerson et al., 2017
whole organism mmp2 expression increased amount, abnormal	WT + MO1-sema6a	standard conditions	Fig. 4 from Emerson et al., 2017
eye decreased size, abnormal	zf460Tg + MO1-sema6a	standard conditions	Fig. 1 from Emerson et al., 2017
optic vesicle apoptotic process increased occurrence, abnormal	zf460Tg + MO1-sema6a	standard conditions	Fig. 5 from Ebert et al., 2014
optic cup cell population proliferation decreased occurrence, abnormal	zf460Tg + MO1-sema6a	standard conditions	Fig. 1 from Emerson et al., 2017
optic vesicle formation decreased process quality, abnormal	zf460Tg + MO1-sema6a	standard conditions	Fig. 5 from Ebert et al., 2014
optic vesicle cell mislocalised, abnormal	zf460Tg + MO1-sema6a	standard conditions	Fig. 5 from Ebert et al., 2014
optic vesicle decreased size, abnormal	zf460Tg + MO1-sema6a	standard conditions	Fig. 5 from Ebert et al., 2014
optic vesicle regionalization decreased process quality, abnormal	WT + MO1-plxna2 + MO1-sema6a	standard conditions	Fig. 7 from Ebert et al., 2014

Citations