Gene

dcdc2b

ID
ZDB-GENE-051113-124
Name
doublecortin domain containing 2B
Symbol
dcdc2b Nomenclature History
Previous Names
  • zgc:123267
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Involved in pronephros development; sensory organ development; and sensory perception of sound. Predicted to colocalize with cortical actin cytoskeleton. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder; autosomal recessive nonsyndromic deafness 66; dyslexia; nephronophthisis 19; and sclerosing cholangitis. Is expressed in otic vesicle. Orthologous to several human genes including DCDC2B (doublecortin domain containing 2B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dcdc2b Human Ortholog
No data available
Associated With dcdc2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003533 Doublecortin domain
Homologous_superfamily IPR036572 Doublecortin domain superfamily
Domain Details Per Protein
Protein Length Doublecortin domain Doublecortin domain superfamily
UniProtKB:A0A8M6Z1P8 454
UniProtKB:A0A8M6Z961 431
UniProtKB:A0A8M6Z9L0 447
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA dcdc2b-201 (1) Ensembl 1,712 nt
mRNA dcdc2b-202 (1) Ensembl 640 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations