Morpholino

MO2-chek1

ID

ZDB-MRPHLNO-080804-1

Name

MO2-chek1

Previous Names

None

Target

chek1 (1)

Sequence

5' - AGGCACAGCCATTATGCAATCTTCG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO2-chek1

Expressed Gene	Anatomy	Figures
chek1	whole organism	Fig. 2 from Sidi et al., 2008
chek2	whole organism	Fig. 2 from Sidi et al., 2008

Phenotype

Phenotype resulting from MO2-chek1

Phenotype	Fish	Figures
embryo development delayed, abnormal	WT + MO2-chek1	Fig. 2 from Sidi et al., 2008
protein phosphorylation disrupted, abnormal	WT + MO2-chek1	Fig. 2 from Sidi et al., 2008
swim bladder decreased size, abnormal	WT + MO2-chek1	Fig. 2 from Sidi et al., 2008

Phenotype of all Fish created by or utilizing MO2-chek1

Phenotype	Fish	Conditions	Figures
whole organism apoptotic, abnormal	WT + MO2-chek1	radiation	Fig. 2 , Fig. 3 from Sidi et al., 2008
mitotic G2 DNA damage checkpoint signaling disrupted, abnormal	WT + MO2-chek1	radiation	Fig. S1 from Sidi et al., 2008
swim bladder decreased size, abnormal	WT + MO2-chek1	standard conditions	Fig. 2 from Sidi et al., 2008
protein phosphorylation disrupted, abnormal	WT + MO2-chek1	standard conditions	Fig. 2 from Sidi et al., 2008
embryo development delayed, abnormal	WT + MO2-chek1	standard conditions	Fig. 2 from Sidi et al., 2008
whole organism apoptotic, abnormal	tp53^zdf1/zdf1 + MO2-chek1	radiation	Fig. 1 , Fig. 2 , Fig. 3 , Fig. S4 from Sidi et al., 2008
myeloid cell decreased amount, abnormal	tp53^zdf1/zdf1 + MO2-chek1	radiation	Fig. 2 from Sidi et al., 2008
mitotic G2 DNA damage checkpoint signaling disrupted, abnormal	tp53^zdf1/zdf1 + MO2-chek1	radiation	Fig. S1 from Sidi et al., 2008
whole organism apoptotic, abnormal	tp53^zdf1/zdf1 + MO2-chek1 + MO4-tp53	radiation	Fig. 2 from Sidi et al., 2008
whole organism apoptotic, abnormal	tp53^zdf2/zdf2 + MO2-chek1	radiation, heat shock	Fig. 2 from Sidi et al., 2008
spinal cord apoptotic, abnormal	tp53^zdf1/zdf1 + MO1-atm + MO2-chek1	radiation	Fig. 4 from Sidi et al., 2008
spinal cord apoptotic, abnormal	tp53^zdf1/zdf1 + MO1-atr + MO2-chek1	radiation	Fig. 4 from Sidi et al., 2008
spinal cord apoptotic, abnormal	tp53^zdf1/zdf1 + MO1-casp2 + MO2-chek1	radiation	Fig. 4 from Sidi et al., 2008
spinal cord apoptotic, abnormal	tp53^zdf1/zdf1 + MO1-casp9 + MO2-chek1	radiation	Fig. 4 from Sidi et al., 2008
spinal cord apoptotic, abnormal	tp53^zdf1/zdf1 + MO1-tp73 + MO2-chek1	radiation	Fig. 4 from Sidi et al., 2008
spinal cord apoptotic, abnormal	tp53^zdf1/zdf1 + MO2-bbc3 + MO2-chek1	radiation	Fig. 4 from Sidi et al., 2008
whole organism apoptotic, abnormal	tp53^zdf1/zdf1 + MO2-chek1 + MO2-chek2	radiation	Fig. S4 from Sidi et al., 2008
spinal cord apoptotic, abnormal	tp53^zdf1/zdf1 + MO2-chek1 + MO3-tp63	radiation	Fig. 4 from Sidi et al., 2008
spinal cord apoptotic, abnormal	tp53^zdf1/zdf1 + MO1-tp73 + MO2-chek1 + MO3-tp63	radiation	Fig. 4 from Sidi et al., 2008

Citations