Morpholino

MO1-cdh5

ID

ZDB-MRPHLNO-070810-2

Name

MO1-cdh5

Previous Names

None

Target

Sequence

5' - TTTACAAGACCGTCTACCTTTCCAA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

Splice site morpholino.

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-cdh5

Expressed Gene	Anatomy	Figures
cdh5	(not) whole organism	Fig. 3 from Nicoli et al., 2007
eef1a1l1	whole organism	Fig. 3 from Nicoli et al., 2007

Phenotype

Phenotype resulting from MO1-cdh5

Phenotype	Fish	Figures
blood circulation arrested, abnormal	zn1Tg + MO1-cdh5	Fig. 3 from Nicoli et al., 2007
blood circulation disrupted, abnormal	AB + MO1-cdh5	Fig. 2 from Mitchell et al., 2010
endocardial cushion morphology, abnormal	AB + MO1-cdh5	Fig. 7 from Chen et al., 2012
heart looping disrupted, abnormal	AB + MO1-cdh5	Fig. 2 from Mitchell et al., 2010
pericardium edematous, abnormal	AB + MO1-cdh5	Fig. 2 from Mitchell et al., 2010
pericardium increased size, abnormal	zn1Tg + MO1-cdh5	Fig. 3 from Nicoli et al., 2007

Phenotype of all Fish created by or utilizing MO1-cdh5

Phenotype	Fish	Conditions	Figures
blood circulation disrupted, abnormal	AB + MO1-cdh5	standard conditions	Fig. 2 from Mitchell et al., 2010
endocardial cushion morphology, abnormal	AB + MO1-cdh5	standard conditions	Fig. 7 from Chen et al., 2012
heart looping disrupted, abnormal	AB + MO1-cdh5	standard conditions	Fig. 2 from Mitchell et al., 2010
pericardium edematous, abnormal	AB + MO1-cdh5	standard conditions	Fig. 2 from Mitchell et al., 2010
pericardium increased size, abnormal	zn1Tg + MO1-cdh5	standard conditions	Fig. 3 from Nicoli et al., 2007
blood circulation arrested, abnormal	zn1Tg + MO1-cdh5	standard conditions	Fig. 3 from Nicoli et al., 2007
cranial blood vessel immature, abnormal	hars^cq34/cq34; s843Tg + MO1-cdh5	standard conditions	Fig. 3 from Ni et al., 2018
cranial vasculature structure, ameliorated	hars^cq34/cq34; s843Tg + MO1-cdh5	standard conditions	Fig. 3 from Ni et al., 2018
endothelial tip cell cell adhesion decreased efficacy, abnormal	s916Tg; ubs18Tg; ubs3Tg + MO1-cdh5	standard conditions	Fig. 2 from Sauteur et al., 2017
cell adhesion involved in sprouting angiogenesis disrupted, abnormal	s916Tg; ubs18Tg; ubs3Tg + MO1-cdh5	standard conditions	Fig. 2 from Sauteur et al., 2017
dorsal longitudinal anastomotic vessel blood vessel development delayed, abnormal	s916Tg; ubs18Tg; ubs3Tg + MO1-cdh5	standard conditions	Fig. 2 from Sauteur et al., 2017

Citations