|
Fig. 7 Heat map diagram showing effects of parental exposure to fluoxetine on monoaminergic neurotransmitters levels of offspring at 8 dpf and 3-month-old. The colors in the heat map represent the deviation from the control offspring, with a gradient of green or red for values below or above the controls, respectively. The number within each cell corresponds to the mean of the results for each parameter normalized as percentage of their respective controls. *p < 0.05, **p < 0.01, ***p < 0.001; [8 dpf: One-way ANOVA with Dunnett's multiple comparison test (5-HT, tryptophan, dopamine, HVA and norepinephrine) or Kruskal Wallis test with Dunn's multiple comparison test (tyrosine); 3-month-old: One-way ANOVA with Dunnett's multiple comparison test (5-HT, tryptophan, dopamine, HVA, tyrosine and norepinephrine)]. Data from 3 independent assays.