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Fig. 3 Isobavachin and phenoxodiol are potent activators of estrogen receptor Dose-response curves in ERα-GFP:PRL-HeLa measuring proportion of cells with an array for (A) E2, isobavachin, and phenoxodiol, (B) isobavachin, bavachin, isobavachalcone, neobavaisoflavone, or (C) phenoxodiol, genistein, ±equol, and daidzein. Dose-response curves in ERα-GFP:PRL-HeLa measuring average dsRed2 FISH intensity for (D) E2, isobavachin, and phenoxodiol, (E) isobavachin, bavachin, isobavachalcone, neobavaisoflavone, or (F) phenoxodiol, genistein, ±equol and daidzein. Dose-response curves in GFPL-ERβ:PRL-HeLa measuring proportion of cells with an array for (G) E2, isobavachin, and phenoxodiol, (H) isobavachin, bavachin, isobavachalcone, neobavaisoflavone, or (I) phenoxodiol, genistein, ±equol and daidzein. Dose-response curves in PRL-ERβ measuring average dsRed2 FISH intensity for (J) E2, isobavachin, and phenoxodiol, (K) isobavachin, bavachin, isobavachalcone, neobavaisoflavone, or (L) phenoxodiol, genistein, ±equol and daidzein. (M) Table including compounds structures and calculated EC50. Error bars represent standard deviation.