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Fig. 6 Estradiol treatment after brain injury tends to increase claudin and tight junction protein gene expression compared to untreated controls. (a–d) Zebrafish males treated with 10−7 M of E2 8 h postinjury (hpi) show an increasing trend in blood–brain barrier (BBB) gene expression 1 day after the lesion (dpi). SW, stab-wounded telencephalon. n = 5 pools of three injured telencephalons.
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Full text @ J. Comp. Neurol.