|
Fig. 3 arid1b mutants display impaired social preference for the social cue. A. Image showing the experimental set-up to collect baseline and post-baseline social preference data. Dividers are taken out following habituation-I (5 min) and baseline (10 min) periods to perform habituation-II (5 min) and post-baseline (10 min) recordings. Data is captured from the virtually defined two rectangular zones on the middle well. B. Comparison of change in SPI across 3 genotypes. A significant difference in the time spent in interaction with the social cue, a zebrafish which is at the same age and size with the experimental animal, among arid1b genotypes (F(2, 81) = 5.40; p = 0.0063) was observed. **p < 0.01. C. Graphs showing SPI difference between baseline and post-baseline recordings in wild type, heterozygous and homozygous arid1b zebrafish. Heterozygous and homozygous animals spent less time in interaction with the social cue compared to the wild type controls. Data in graph B is presented as mean + 95% CI for group averages. Dots indicate individuals and red data represent mean ± 95% CI. Total n = 85, arid1b +/+ n = 20, arid1b ± n = 47, arid1b −/− n = 18. n: number of animals. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)