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Fig. 11 Change in B-cell subtypes in response to SVCV infection. (A) tSNE nonlinear clustering was used to visualize the differences in the classification results of B populations between the control group (PBS) and the SVCV-infected group. (B) Histogram illustrating the differences in B-cell ratios between the control group and the SVCV-infected group. (C) Heatmap of the differentially expressed genes for apoptosis, ferroptosis, necroptosis, and autophagy in the cluster 0 B-cell subset between the control group and the SVCV-infected group. (D) Top 20 most significant KEGG pathways for the cluster 0 B-cell subset.