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FIGURE 1
Protein–protein interaction (PPI) network of NRG1 and RET. Proteins and signaling pathways significantly related to NRG1 and RET were illustrated. The size of the surrounded nodes represents the ranking of the relationships. The interconnected lines represent the predicted networks (physical interactions, co-expression, predicted, co-localization, genetic interactions, pathway, and shared protein domains). The color of the surrounded nodes represents the predicted function of the genes (axonogenesis, neuron projection guidance, ERBB signaling pathway, regulation of protein kinase B signaling, protein tyrosine kinase activity, transmembrane receptor protein kinase activity).