Fig. 3
24-hour expression profiles of core clock genes in zebrafish organs. 24-hour (a) arntl1b, (b) clocka, (c) per3, and (d) cry1ba expression levels in zebrafish heart, and (e) arntl1b and (f) per3 in kidneys between control and HF ((a–d) N = 9, (e) N = 3, (f) N = 6 zebrafish/group/ZT; mean ± SEM), normalised against control ZT0. Statistical significance of cosinor rhythmicity of delta Ct values per group is indicated at the top left graph corner: ∗P < 0.05, ∗∗∗∗P < 0.0001. Horizontal bar indicates lights-on (=white; ZT0) and lights-off (=black; ZT14) period. arntl1b = Aryl Hydrocarbon Receptor Nuclear Translocator Like 1 b. Other abbreviations as in Fig. 2.