ZFIN Image: Snodgrass et al., 2023, Fig. 5.

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Figure Caption

Fig. 5.

Combined low-dose mTOR and MEK inhibition prevents abnormal trunk vasculature and excess kugel formation in eng^mu130 zebrafish embryos. (A-C) Neither 2 µM rapamycin (RAP) nor 7.5 µM PD0325901 (PD0) alters the vascular phenotype of eng^mu130 mutants, but combined treatment resulted in normalised DA and PCV diameters, as well as reduced kugel formation in eng^mu130 zebrafish embryos. *P<0.05, ***P<0.001, ****P<0.0001; ns, not significant (two-way ANOVA with Tukey post-hoc test, 10-14 animals/group).

Figure Data

Phenotype details

Acknowledgments

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