ZFIN Image: Shibata et al., 2022, Figure 6

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Figure Caption

Figure 6

Lipidomic analyses of lpgat1 mutant zebrafish. Lipids were collected at 7 days post fertilization from a single zebrafish larva obtained from crossing an lpgat1^+/− male with an lpgat1^+/− female and analyzed for phosphatidylcholine (PC, A), phosphatidylethanolamine (PE, B), phosphatidylinositol (PI, C), phosphatidylserine (PS, D), phosphatidylglycerol (PG, E), and phosphatidic acid (PA, F) by LC–MS/MS. Genotypes of each larva were determined by PCR after a lipid sample was collected. The fish were obtained from three independent crosses. The numbers of samples were n = 18 for lpgat1^+/+, n = 19 for lpgat1^+/− and n = 7 for lpgat1^−/−. Error bars are S.D. Statistically significant differences are marked with asterisks. *p < 0.05; **p < 0.01; ***p < 0.001. Two-way ANOVA, Bonferroni’s multiple comparison test was used. For molecular species with low abundance, the relative abundance of each molecular species is shown in Supplementary Fig. S9.

Figure Data

Phenotype details

Acknowledgments

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