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Fig. 7
Systematic proteomics analysis of developmental changes in protein expression in control and 2,4-DAB (500 µM) treated zebrafish larvae. A DEPs were identified in by comparing 4 dpf and 2 dpf samples in control and 2,4-DAB-treated larvae. Venn diagram showing DEP overlap between control and the 2,4-DAB treatment. B Canonical pathways impacted during development from 2 to 4 dpf in control and 2,4-DAB samples. C Predicted upstream regulators. D Diseases and biological functions. The red- or blue-colored rectangles in each column indicate the z-score activities for each analysis. Red shading indicates predicted activation and blue shading indicates predicted inhibition. This heat map represents the activated of inhibited z-scores that were greater than the absolute value of 2