Figure 4
GNP-mediated DTBR significantly decreased HNCC proliferation in vivo. Groups of 15–20 zebrafish larvae were used for each time point and treatment group, 50–100 cells were injected into the yolk sac of each fish, and the number of fluorescent cells was quantified ex vivo. Xenografted cells were quantified at baseline (0 days post radiation (dpr)) and 3 dpr after treatment with 8 Gy from the STB or DTB. Results are represented as fold change of the unirradiated control cells (No RT). (