ZFIN Image: Mullapudi et al., 2019, Fig. 2

Image

Figure Caption

Fig. 2 dnVegfaa exerts a dose-dependent effect on β-cell dispersion. (A) β-Cells (green) from 48 hpf Tg(ins:GFP) embryos with mosaic Tg(ins:dnvegfaa) expression. The percentage of β-cells expressing dnvegfaa (magenta) is indicated, as is the severity of islet dispersion (intact, moderate or severe; white). (B) Quantification of embryos displaying varying severity of islet dispersion. (C-J) Immunostaining for insulin (β-cells, red) and endothelial cells (green) in 48 hpf Tg(fli:GFP) embryos, in combination with the indicated transgenic or mutant line, n=3-5 animals per genotype. Maximum intensity projections are presented. A, anterior; D, dorsal.

Figure Data

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development