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FIGURE 10 Ocular development in FD larvae and response to retinoic acid. Eye size (A) and OMR (B) of FD larvae with/without RA treatment were estimated at 5 and 7 dpf, respectively. The distributions of rhodopsin transcripts in larvae with/without RA supplementation were characterized with WISH at 3 dpf (C) and quantified (E). The distribution of aldh1a2 and aldh1a3 transcripts in larvae with/without RA supplementation were characterized with WISH at 30 hpf (D) and quantified (F). C, control; M, mFD; S, sFD. Statistical data are shown in mean ± SEM for (A,E) and percentage in a group for (B,F). ***p < 0.001; *p < 0.05.