Gene
aldh1a2
- ID
- ZDB-GENE-011010-3
- Name
- aldehyde dehydrogenase 1 family, member A2
- Symbol
- aldh1a2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have aldehyde dehydrogenase (NAD+) activity. Involved in several processes, including animal organ development; face morphogenesis; and myelination. Is expressed in several structures, including head; heart; immature eye; mesoderm; and pleuroperitoneal region. Orthologous to human ALDH1A2 (aldehyde dehydrogenase 1 family member A2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 135 figures from 103 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 40 figures from 24 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Diaphragmatic hernia 4, with cardiovascular defects | 620025 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR016160 | Aldehyde dehydrogenase, cysteine active site |
Conserved_site | IPR029510 | Aldehyde dehydrogenase, glutamic acid active site |
Domain | IPR015590 | Aldehyde dehydrogenase domain |
Homologous_superfamily | IPR016161 | Aldehyde/histidinol dehydrogenase |
Homologous_superfamily | IPR016162 | Aldehyde dehydrogenase, N-terminal |
Homologous_superfamily | IPR016163 | Aldehyde dehydrogenase, C-terminal |
Domain Details Per Protein
Protein | Length | Aldehyde dehydrogenase, C-terminal | Aldehyde dehydrogenase, cysteine active site | Aldehyde dehydrogenase domain | Aldehyde dehydrogenase, glutamic acid active site | Aldehyde dehydrogenase, N-terminal | Aldehyde/histidinol dehydrogenase |
---|---|---|---|---|---|---|---|
UniProtKB:Q90XS8
|
518 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
aldh1a2-201
(1)
|
Havana | 3252 nt | |
ncRNA |
aldh1a2-002
(1)
|
Havana | 699 nt |
Interactions and Pathways
No data available
Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
---|---|---|---|---|---|---|---|
Ab1-aldh1a2 | polyclonal | IgG | Rabbit |
|
GeneTex
|
15 |
Plasmids
No data available