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Figure 7 - figure supplement 2

ID: ZDB-IMAGE-210607-41
Source: Figures for Li et al., 2021

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Figure Caption

Figure 7 - figure supplement 2 Inhibiting Rho kinase blocks caudal venous plexus (CVP) cavernoma formation in <italic toggle='yes'>ccm2</italic> CRISPR zebrafish.

At 24 hpf, ccm2 CRISPR embryos were treated with 45 μM Y-27632(Tocris) in egg water as described by Uehata et al. (Nature:389 (1997) pp. 990–994) and controls were treated with 1% DMSO. At 2 days post fertilization (dpf), in contrast to DMSO-treated embryos, no embryos treated with Y-27632 exhibited CVP dilation (**p=0.0098) or other obvious developmental anomalies. Total number of embryos in each group is indicated above the bars. Two-tailed Fisher’s exact test was used for comparisons.

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Acknowledgments

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