ZFIN Image: Takahashi et al., 2020, Fig. 4

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Figure Caption

Fig. 4 Development of neural crest cells is severely affected in kzt embryos. Offspring from crosses between kzt heterozygotes (kzt+/–) were stained for the expression of neural crest cell (NCC) marker genes. Lateral views are shown with anterior to the left and dorsal to the top, whereas dorsal views are with anterior to the left except for the last two (j, j’), in which anterior is to the top. As little morphological disorder was recognized until late somitogenesis, kzt+/– phenotypes were assessed based on whether their ratios were approximately one-quarter. The percentages of abnormal embryos and total embryo numbers examined are shown at the bottom left. After 24 hpf, sibling embryos (kzt+/–) and homozygotes (kzt–/–) were identified morphologically. anc, anterior neural crest; cnc, cranial neural crest; fb, forebrain; nb, neural plate border; pa, pharyngeal arches; p1–5, pharyngeal arch 1–5; tnc, trunk neural crest cell. Scale bars, 200 μm.

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Acknowledgments

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Reprinted from Developmental Biology, 472, Takahashi, K., Ito, Y., Yoshimura, M., Nikaido, M., Yuikawa, T., Kawamura, A., Tsuda, S., Kage, D., Yamasu, K., A globin-family protein, cytoglobin 1, is involved in the development of neural crest-derived tissues and organs in zebrafish, 1-17, Copyright (2020) with permission from Elsevier. Full text @ Dev. Biol.