ZFIN Image: Brastrom et al., 2021, Figure 1

Image

Figure Caption

Figure 1 Mutation of rbm24a phenocopies morpholino knockdown. (A) Schematic for genetic structure of Rbm24a, with the RNA recognition motif (RRM) in blue and the Ala-rich region in green. The red line indicates the site of the Alt-R CRISPR/Cas0 mutation. (B) Uninjected control 4 dpf embryo with wild type morphology. (B’) Detail of eye shown in B. (C) and (D) are Alt-R CRISPR/Cas9-injected embryos showing the variation of the phenotypes. (C’) and (D’) are detail of eyes found in C and D, respectively. (E) Graph of uninjected and CRISPR-injected F0 embryos. (F) Synthego ICE analysis of mutations found in F0 mutants. Indels are listed. Images taken at 33×.

Figure Data

Phenotype details

Acknowledgments

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