ZFIN Image: van Wijk et al., 2020, FIGURE 1

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Figure Caption

FIGURE 1

Experimental study design. Fertilized eggs at 0 days post fertilization (dpf) were harvested and injected with 200 CFU Mycobacterium marinum at 1 dpf. After 2 days of establishing the infection, fluorescence imaging was performed (orange arrow; n ≥ 20 larvae per group), and the treatment with isoniazid dissolved in the external treatment medium (0.25–10‐fold MIC, MIC = 15 mg·L⁻¹, and control) was started. Fluorescence imaging was repeated daily (orange solid arrows). In satellite larvae groups, destructive homogenate and blood samples for internal isoniazid exposure quantification were taken from 0 to 50 h of treatment (blue dashed arrows)

Acknowledgments

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