ZFIN Image: Liu et al., 2020, Fig. 6

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Figure Caption

Fig. 6 pax1a- and pax1b-deficient embryos display decreased or absent dlx2a and hand2 expression in pharyngeal arches. Reduced expression of dlx2a (D) or hand2 (I) as well as absence of dlx2a (E) or hand2 (J) in the posterior pharyngeal arches (pa) was identified in 0.75 ng pax1a MO-injected pax1b−/− mutant embryos compared to uninjected pax1b−/− mutant (C, H), wild types (WT; A, F) or 0.75 ng pax1a MO-injected wild types (B, G) at 36 hpf. Similar defects in expression of dlx2a (L) or hand2 (N) in the posterior pharyngeal arches were also identified in pax1a−/−; pax1b−/− double mutants compared with sibling controls (i.e., pax1a+/−; pax1b−/− or pax1a+/+; pax1b−/−) (K, M) at 36 hpf. Asterisks indicate reduced or absent expression. Affected embryos per total number of analyzed embryos are shown. Scale bars represent 100 μm.

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Acknowledgments

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Reprinted from Mechanisms of Development, 161, Liu, Y.H., Lin, T.C., Hwang, S.L., Zebrafish Pax1a and Pax1b are required for pharyngeal pouch morphogenesis and ceratobranchial cartilage development, 103598, Copyright (2020) with permission from Elsevier. Full text @ Mech. Dev.