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Fig. S8
si:ch73-299h12.3, a paralogue of bif1, induces cyclopia but not dorsalization. A. Protein alignment between bif1 and si:ch73-299h12.3 (h12.3). The protein similarity is 58,2%. The red lines represent the C2H2 domains of bif1. B. h12.3 is, similar to bif1, expressed and in the posterior LPM and its expression is lost in cloche mutant. C. Bright field pictures of embryos, at 1dpf and 5dpf, injected or not with h12.3 mRNA. Red circles mark the eyes; in h12.3-injected embryos, only one cyclopic eye is formed. D. WISH against gata1 at 12hpf in embryos injected with h12.3
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