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Fig. 5
Expression of fgf19 is disrupted due to loss of foxc1function. fgf19 expression is found ubiquitously in the head at 20 hpf (A), and is reduced in foxc1b −/− injected with foxc1amorpholinos (B). The expression of two early retinal homeoboxgenes (rx2 and rx3) is not altered in these embryos (rx2, 16 somites C, D, rx3, 10 somites, E, F). Lateral views (A, B, E, F) and dorsal views (C, D).
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Reprinted from Vision Research, 156, Umali, J., Hawkey-Noble, A., French, C.R., Loss of foxc1 in zebrafish reduces optic nerve size and cell number in the ganglion cell layer, 66-72, Copyright (2019) with permission from Elsevier. Full text @ Vision Res.