ZFIN Image: Chrispell et al., 2018, Fig. 5

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Figure Caption

Fig. 5 Recovery of the native ERG b-wave to successive stimuli in grk knockout zebrafish larvae. (A) Representative ERG waveforms of untreated, dark-adapted larvae subjected to successive stimuli using a dual flash paradigm of a 20-ms flash of saturating white light (1000 cd/m2) with an interstimulus interval (ISI) of 2 s. Vertical black dotted lines indicate the time of stimulus. (B) Data are plotted as the ratio of the maximum b-wave response amplitude of the second stimulus to that of the initial stimulus for ISIs ranging from 0.75 s to 5 s. A linear mixed model analysis of covariance found no significant effect of genotype when compared to wildtype for grk1b^−/− (F_[1,14] = 1.2; P = 0.2879) or grk7a^−/− larvae (F_[1,17] = 3.3; P = 0.0889). Error bars represent SEM.

Figure Data

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Invest. Ophthalmol. Vis. Sci.