ZFIN Image: McMillan et al., 2018, Fig. 5

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Figure Caption

Fig. 5

In evx1^−/− loss-of-function mutants, expression of hoxa13a but not pthlha persists in presumptive joint cells. (A) Wild-type fins possess joints (white arrowheads). (B,C) ISH on longitudinal cryosections of 4 dpa wild-type regenerates reveals hoxa13a (B) and pthlha (C) expression in joint cells (blue arrowheads). (D) In evx1^−/− mutants joints are lost. (E,F) Longitudinal cryosections of 4 dpa evx1^−/− mutant regenerates indicate hoxa13a (E) is expressed in presumptive joint cells but pthlha is not (F). Numbers in each panel represent the number of sections with the expression pattern over the total number of sections analyzed. Scale bars: 200 μm (in A for A,D); 50 μm (in B for B,C,E,F).

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Acknowledgments

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