Gene
hoxa13a
- ID
- ZDB-GENE-990415-5
- Name
- homeobox A13a
- Symbol
- hoxa13a Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Exhibits DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in negative regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in Guttmacher syndrome and hand-foot-genital syndrome. Is expressed in several structures, including central nervous system; gut; notochord; pectoral fin; and pectoral fin bud. Orthologous to human HOXA13 (homeobox A13).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 16 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Guttmacher syndrome | Alliance | ?Guttmacher syndrome | 176305 |
| hand-foot-genital syndrome | Alliance | Hand-foot-genital syndrome | 140000 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Anterior-posterior axis regulatory homeobox | Homedomain-like superfamily | Homeobox, conserved site | Homeobox protein Hox1A3 N-terminal | Homeodomain |
|---|---|---|---|---|---|---|
|
UniProtKB:A3KNK0
|
310 | |||||
|
UniProtKB:Q6W990
|
310 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
hoxa13a-201
(1)
|
Ensembl | 1,669 nt |
Interactions and Pathways
No data available
Plasmids