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Fig. 8
Pax2a is required for prosensory but not proneural expansion. (A–H) Dorsolateral views (anterior to the left) showing otic expression of atoh1a (A–D) and neurog1 (E–H) at 24 hpf in control embryos (A, E), pax2a-morphants (C, G), hs:sox2/hs:sox2 homozygotes (B, F) and hs:sox2/hs:sox2 homozygotes injected with pax2a-mo (D, -H). Embryos were heat shocked at 12.5 hpf, 39 °C for 60 min. Otic vesicle borders are outlined in all images.
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Reprinted from Developmental Biology, 435(1), Gou, Y., Vemaraju, S., Sweet, E.M., Kwon, H.J., Riley, B.B., sox2 and sox3 play unique roles in development of hair cells and neurons in the zebrafish inner ear, 73-83, Copyright (2018) with permission from Elsevier. Full text @ Dev. Biol.