ZFIN Image: Barske et al., 2018, Fig. S4

Image

Figure Caption

Fig. S4

Additional gene expression patterns in nr2f2; nr2f5 mutants. (A) pitx2 and meis2b (magenta) were classified as Nr2f-activated genes by RNAseq but were not consistently altered in nr2f2; nr2f5 mutants. pitx2 was minimally expressed in dlx2a+ arch NCCs (green) but detected in the adjacent ocular mesenchyme (oc). meis2b was mainly confined to the hyoid arch. (B) jag1b expression (magenta) in non-maxillary dorsal cells was largely unaffected in Nr2f mutants. (C) Frontonasal (fn) NCC expression of alx1 and gata3 (magenta) was preserved in nr2f2; nr2f5 mutants. (D) The neurocranium, including the NCC-derived anterior portion, was slightly smaller but otherwise typically formed in nr2f2; nr2f5 mutants. Scale bars: A-C = 20 μm, D = 50 μm.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Cell, 44(3), Barske, L., Rataud, P., Behizad, K., Del Rio, L., Cox, S.G., Crump, J.G., Essential Role of Nr2f Nuclear Receptors in Patterning the Vertebrate Upper Jaw, 337-347.e5, Copyright (2018) with permission from Elsevier. Full text @ Dev. Cell