ZFIN Image: Kroeger et al., 2017, Fig. 8

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Figure Caption

Fig. 8

zepandbrca2^ZM_00057434fail to complement one another. (A) Gene expression analysis of the interrenal marker nr5a1a in WT, zep -/-, brca2^ZM_00057434 -/- and compound heterozygous brca2^ZM_00057434+/-; zep +/- mutants revealed that brca2^ZM_00057434 -/- have a modest but (B) statistically significant elevation in the area of nr5a1a expression that was similar to compound heterozygous embryos. Embryos are shown in dorsal views with insets showing digital zoom of 150%, where black boxes demarcate the cervical region where the interrenal gland develops. Asterisks (*) indicate p < 0.05, (**) p < 0.01 using student T-test.

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Acknowledgments

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Reprinted from Developmental Biology, 428(1), Kroeger, P.T., Drummond, B.E., Miceli, R., McKernan, M., Gerlach, G.F., Marra, A.N., Fox, A., McCampbell, K.K., Leshchiner, I., Rodriguez-Mari, A., BreMiller, R., Thummel, R., Davidson, A.J., Postlethwait, J., Goessling, W., Wingert, R.A., The zebrafish kidney mutant zeppelin reveals that brca2/fancd1 is essential for pronephros development, 148-163, Copyright (2017) with permission from Elsevier. Full text @ Dev. Biol.