Image
|
Figure Caption
Fig. S3
Altering EphrinB1 and EphB3b levels leads to defects in lamellipodia orientation and hepatoblast positioning. Related to Figure 6.
(A-B”) Conditional expression of UAS:ephrinB1 causes a posterior accumulation of hepatoblasts and morphological defects of the liver domain (B-B''). (C) Hepatoblast lamellipodia are oriented with respect to the anteroposterior axis. Expression of EphrinB1 and EphrinB16F randomises lamellipodia orientation in comparison to control and MO-ephrinB1 embryos, and similar to compromised EphB3b function (see Figure 6H).
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Reprinted from Developmental Cell, 39, Cayuso, J., Dzementsei, A., Fischer, J.C., Karemore, G., Caviglia, S., Bartholdson, J., Wright, G.J., Ober, E.A., EphrinB1/EphB3b Coordinate Bidirectional Epithelial-Mesenchymal Interactions Controlling Liver Morphogenesis and Laterality, 316-328, Copyright (2016) with permission from Elsevier. Full text @ Dev. Cell