ZFIN Image: Xu et al., 2016, Fig. S2

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Figure Caption

Fig. S2

Microglial Precursors Enter the Optic Tectum via Non-circulation route, related to Figure 2

(A) Dorsal view of the optic tectum of Tg(mpeg1:loxP-DsRedx-loxP-GFP) zebrafish embryos injected with or without the tnnt2a morpholno. The number of the optic tectum-resident microglia only slightly decreased in the 3 dpf tnnt2a morphants (MO) but is drastically reduced in the 6 dpf tnnt2a morphants. The optic tectum is indicated by dashed lines.

(B) Quantification of the optic tectum-resident microglia number in WT embryos and tnnt2a morphants. Error bars represent mean SEM. **: p<0.01. ***: p<0.001. (n=8 for both WT and morphants at 3 dpf and 6 dpf)

Acknowledgments

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Reprinted from Developmental Cell, 38(2), Xu, J., Wang, T., Wu, Y., Jin, W., Wen, Z., Microglia Colonization of Developing Zebrafish Midbrain Is Promoted by Apoptotic Neuron and Lysophosphatidylcholine, 214-22, Copyright (2016) with permission from Elsevier. Full text @ Dev. Cell